Muhammad's Visions and struggle to fight depression

The first vision was followed by a considerable period, during which Muhammad suffered much mental depression. Only Almighty Allah knows what Muhammad must have been thinking and feeling at that time. He may have been worried about his visions, uncertain as to how the majority of the Makkans would treat Allah's blessing, since their own interests were at stake. The Makkans, at that time, relied heavily on trade that revolved around polytheistic and pagan rituals of false idols and statues and other things that they worshiped. One can't contemplate his future and responsibilities to the people of the world, as well as the challenges that Allah Almighty had chosen him for.